Management of Gout

• Uricosuric Agents

• • Probenecid (ASA an antagonist); inhibits resportion of uric acid thus increases excretion of uric acid
  • Sulfinprazone (anturan) to block resorption uric acid
  • Need high fluid intake, alkaline urine

• Xanthine-oxidase inhibitors decrease uric acid production

• • Allopurinal (zyloprim); may cause agranucytosis
  • Need high fluid intake, and alkaline urine

Previous slide

Back to first slide

View graphic version