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Human immune
response
Gene specifying herpes
simplex surface protein
Harmless vaccinia
(cowpox) virus
Herpes simplex virus
2. Herpes simplex
gene
is isolated.
3. Vaccinia DNA
is extracted
and cleaved.
4. Fragment containing
surface gene
combines with
cleaved vaccinia DNA.
5. Harmless engineered
virus (the vaccine)
with
surface like
herpes simplex is
injected into the
human body.
6. Antibodies directed
against herpes
simplex viral coat
are made.
1. DNA is
extracted.
Construction of a subunit vaccine against herpes simplex: