77
Copyright © The McGraw-Hill Companies, Inc. Permission required for
reproduction or display.
Human immune
response
Gene specifying herpes
simplex surface protein
Harmless
vaccinia
(cowpox) virus
Herpes simplex virus
2. Herpes simplex
gene
is isolated.
3. Vaccinia DNA
is extracted
and cleaved.
4. Fragment containing
surface gene
combines with
cleaved vaccinia
DNA.
5. Harmless engineered
virus (the vaccine)
with surface like
herpes simplex is
injected into the
human body.
6. Antibodies directed
against
herpes
simplex viral coat
are made.
1. DNA is
extracted.
Construction of a subunit vaccine
against herpes
simplex: